Bruton&’s tyrosine kinase
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Bruton's tyrosine kinase — (or Btk) is a type of kinase enzyme implicated in the primary immunodeficiency disease X linked agammaglobulinemia (XLA). Its exact mechanism of action remains unknown, but it plays a crucial role in B cell maturation as well as mast cell… … Wikipedia
Bruton agammaglobulinemia (disease) tyrosine kinase — Bru·ton agammaglobulinemia (disease), tyrosine kinase (brooґtən) [Col. Ogden Carr Bruton, American pediatrician, 1908–2003] see X linked agammaglobulinemia, under agammaglobulinemia, and see Bruton tyrosine kinase … Medical dictionary
Bruton tyrosine kinase — (BTK) Bru·ton ty·ro·sine ki·nase (BTK) (brooґtən tiґro sēn kiґnās) a nonreceptor tyrosine kinase (non specific protein tyrosine kinase, q.v.) that plays an important role in signaling in B cell activation and differentiation;… … Medical dictionary
Non-specific protein-tyrosine kinase — In enzymology, a non specific protein tyrosine kinase (EC number|2.7.10.2) is an enzyme that catalyzes the chemical reaction:ATP + a [protein] L tyrosine ightleftharpoons ADP + a [protein] L tyrosine phosphateThus, the two substrates of this… … Wikipedia
Bruton (disambiguation) — Bruton may refer to:Places* Bruton, a village and civil parish in Somerset, EnglandPeople* John Bruton, Ambassador of the European Union to the United States of America. * Richard Bruton, Opposition Spokesperson on Finance in Ireland. * Bill… … Wikipedia
Ogden Bruton — Ogden Carr Bruton Ogden Carr Bruton (born June 14, 1908 in Mount Gilead, North Carolina; died January 20, 2003) was a pediatrician and chief of pediatrics at Walter Reed Army Hospital, where he organized the first pediatric residency at this… … Wikipedia
Bruton-Tyrosinkinase — Masse/Länge Primärstruktur 658 Aminosäuren … Deutsch Wikipedia
Protein kinase D1 — Protein kinase D1, also known as PRKD1, is a human gene.cite web | title = Entrez Gene: PRKD1 protein kinase D1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=5587| accessdate = ] PBB Summary section title … Wikipedia
Btk — • Bruton s tyrosine kinase … Dictionary of medical acronyms & abbreviations
btk — (= Bruton&’s tyrosine kinase) Tyrosine kinase of tec family, defective in Bruton&’s agammaglobulinaemia. Mutations in btk lead to B cell immunodeficiencies XLA in humans, Xid in mice. Overexpression of btk enhances calcium influx following B cell … Dictionary of molecular biology
